Category Archives: Innovation

Mission Aligned: Helmsley Charitable Trust and StartUp Health on T1D Moonshot



Welcome back to StartUp Health NOW, the podcast where we hear directly from the entrepreneurs and innovators who are transforming health.

Typically on this show we talk to founders of startups. We’re all about understanding what’s new and next in health, and that often means talking to the people who are in the early days of creating a product or business. Most early-stage startups – healthcare or otherwise – have one thing in common. They need money. It takes a long time to get a healthcare business profitable, and so founders need outside funds to get an idea off the ground, complete their research, or scale up.

That brings us to this week’s guest, David Panzirer, Trustee at the Helmsley Charitable Trust. To put it in simple startup terms, David is a funder. The Helmsley Charitable Trust is an $8 billion dollar philanthropy renowned for its work funding healthcare research and innovative programs.

Of course David’s a lot more than a funder. He’s a father, for one thing, a fact that’s driven his work more than anything else. David’s also a firebrand and an instigator in an industry that often needs a little push in the right direction.

The reason for our interview, which took place at a recent health tech event, is that the Helmsley Charitable Trust has been the anchor partner for StartUp Health’s Type 1 Diabetes Moonshot, and David has been instrumental in getting that effort off the ground. He’s been part of our T1D Impact Board and has met with founders on multiple occasions to give them invaluable feedback and advice.

In this episode, we talk about the wild west of conversational AI, promising new T1D therapeutics, rural medicine, and why Helmsley has positioned itself as a high risk/high reward funder.

Let’s get into it.



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Gamification in Healthcare: How Two Founders Are Using Games to Heal



This week, we’re talking about gamification in healthcare. Gamification has been a popular buzzword in tech and in health, but it just means using elements we associate with games in non-game contexts. It means capitalizing on the motivations we find in games through things like progress updates and level-up badges to change behaviors and get us to do things that are going to be good for our health.

Today on the show, we’re talking to two founders who are gamifying the healthcare experience in two unique ways.

The first conversation is with Raj Amin, CEO & Co-founder of Arcade Therapeutics, a company that has been in the StartUp Health community since TK. They are a science-first game studio developing games that act like medicine, focusing on mental health. We’ll hear exactly what they’re building and why clinical research is key to their approach.

Then we’ll hear from Farhaneh Ahmadi, PhD, CEO & Co-founder of eddii, a company that is part of our T1D Moonshot. She and her team are using mobile gaming elements to help young people with their Type 1 diabetes management. Her company uses a character named eddii that talks to the user, tells them stories, and plays games with them – making it more relatable and more enjoyable to manage diabetes.

Listen in to learn more about these innovative approaches to improving health.

 


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Innovating in Alzheimer’s disease? Contact us to learn how you can join our Alzheimer’s Moonshot.
Passionate about Type 1 diabetes? Contact us to learn how you can join our T1D Moonshot.
Looking to break down health barriers? Contact us to learn how you can join our Health Equity Moonshot
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Why the CEO of the American Diabetes Association (ADA) Joined StartUp Health’s Health Moonshot Impact Board



Since 2020, Charles “Chuck” Henderson has led the American Diabetes Association (ADA) as CEO. In 2023, he joined StartUp Health’s Health Moonshot Impact Board, a unique, multi-disciplinary group of stakeholders passionate about advancing health innovation. On the Health Moonshot Impact Board, Henderson joins top thought leaders like Dr. Toby Cosgrove (former CEO, Cleveland Clinic) and Sue Siegel (former CEO, GE Ventures).

In this StartUp Health NOW episode, StartUp Health’s Logan Plaster sat down with Henderson to learn about his priorities in leading the ADA and why it was important to him to join StartUp Health’s moonshot community.


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Want more content like this? You can subscribe to the podcast as well as other health innovation updates at startuphealth.com/content.
Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.

Looking to break down health barriers? If you’re an entrepreneur or investor, contact us to learn how you can join our Health Equity Moonshot.
Passionate about Type 1 diabetes? If you’re an entrepreneur or investor, contact us to learn how you can join our T1D Moonshot.


No More Suffering in Silence: Meet Two Founders Tackling Gut Health



On this week’s StartUp Health NOW episode, we’re talking about the future of gut health with Jeff Glueck, CEO & Co-founder of Salvo Health, and Swathi Arulguppe, CEO & Founder at BetterMeal AI.

There’s no doubt gut health is having a moment.

For a long time, health issues in the gut, like irritable bowel syndrome and Crohn’s disease, were met with outdated pamphlets about diets. The result was millions of people suffering in silence with painful, life-limiting conditions.

It’s not that GI doctors didn’t want to help. There just didn’t seem to be a lot that they could do.

Thankfully our understanding of the importance of gut health – and its connection to mental health and whole health – has resulted in a wave of innovation. And on this podcast episode, we’ll talk to some amazing entrepreneurs working to break this cycle and bring relief to patients.

Our first guest, Jeff Glueck was the CEO of Foursquare before he co-founded Salvo Health. He’s taking on gut health from two innovative angles.

The first is through the establishment of a digital clinic which makes specialty GI care available to patients at scale and on demand. Second, Glueck and his team are capitalizing on the latest research connecting gut health to mental health and other conditions. This connection between the gut microbiome and whole health is just exploding and Salvo is helping patients stay on the cutting edge.

Then we’ll check in with Swathi Arulguppe, CEO & Founder of BetterMeal AI.

You’ll hear how Arulguppe has taken her own journey with a debilitating GI condition, combined it with her passion for data, and built a platform for helping deliver AI-driven personalized meal recommendations to patients. By understanding the biological connections between human gut and food at the deepest level, she has built an app that helps guide its users on how to best manage their gut health through their nutrition.

Let’s jump in and find out where we are in gut health innovation.

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Want more content like this? You can subscribe to the podcast as well as other health innovation updates at startuphealth.com/content.
Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.

Looking to break down health barriers? If you’re an entrepreneur or investor, contact us to learn how you can join our Health Equity Moonshot.
Passionate about Type 1 diabetes? If you’re an entrepreneur or investor, contact us to learn how you can join our T1D Moonshot.


10 Years Later: A Health Tech Investor Reflects on Her Early Days at StartUp Health



Ten years ago, Irem Rami became one of the first Fellows to join StartUp Health. In her role she helped vet the very first companies to join our community. That was back when it seemed very audacious indeed to have a goal of supporting 1000 healthcare startups. A few years later and we’ve now welcomed 500 startups into the community and are still going strong. In that time Rami moved on, went to business school, and is now a principle health investor at Norwest, a $3B multi-stage fund.

We called up Rami up for this StartUp Health NOW podcast episode to give us that decade look back – you know, it’s hard to understand where you’re going if you don’t know where you came from. She’s got a unique perspective on the durability of the StartUp Health vision and what it means to chase the same seemingly impossible dream for more than 10 years.

We also wanted to hear Rami’s advice for health innovators seeking to raise funds in this difficult market. She evaluates opportunities on a daily basis and had some sage advice to share for our listeners.

Enjoy the episode.

FundersBecome a Health Moonshot Champion
Want more content like this? You can subscribe to the podcast as well as other health innovation updates at startuphealth.com/content.
Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.

Looking to break down health barriers? If you’re an entrepreneur or investor, contact us to learn how you can join our Health Equity Moonshot.
Passionate about Type 1 diabetes? If you’re an entrepreneur or investor, contact us to learn how you can join our T1D Moonshot.


How Two Founders Are Using AI to Tackle Wasteful Healthcare Spending



On this StartUp Health NOW episode, we’re talking about wasteful spending in healthcare. This is one of those topics that’s hard to put in perspective. The institute of medicine says that 30% of healthcare spending could be categorized as wasteful, putting the total tab north of $750 million. It could be a trillion dollars.

Health insurance premiums are up 7% year over year, according to Health Affairs. Analysts point to inflation as a strong cause, but this nearly trillion dollars in unnecessary spending isn’t helping the equation.

Bottom line, healthcare costs are out of control and driving many people into medical bankruptcy. If 30% of healthcare spending is unnecessary, we’ve got to get this under control. Thankfully, we’ve got founders in the StartUp Health community who are passionate about this issue.

Jude Odu, CEO & Founder of Health Cost IQ, and Pinaki Dasgupta, CEO & Founder of Hindsait, will help us understand what constitutes wasteful spending and how advances in AI allow us to root it out at the source.

This is the kind of innovation that takes some courage, because pointing out to a hospital that they’re double billing or telling an insurer that they’re making massive errors doesn’t make you popular with either party. But it’s got to be done if we’re going to get overall health costs under control.

Enjoy the episode.

FundersBecome a Health Moonshot Champion
Want more content like this? You can subscribe to the podcast as well as other health innovation updates at startuphealth.com/content.
Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.

Looking to break down health barriers? If you’re an entrepreneur or investor, contact us to learn how you can join our Health Equity Moonshot.
Passionate about Type 1 diabetes? If you’re an entrepreneur or investor, contact us to learn how you can join our T1D Moonshot.


Thriving Seniors: How These Founders Are Upgrading Senior Care from Early Disease Detection to Care Coordination




Food as Medicine: The Next Wave of Tech-Enabled Nutrition



At StartUp Health we’re all about what’s new and what’s next in health, and that often means talking about cutting-edge technology. But sometimes the most radical way to improve is also the simplest. One example? Our food.

This week, as we head into Thanksgiving in the United States, we’re talking about the role food plays in managing not just our weight and fitness, but actual chronic diseases. Some people use the term ‘Food as Medicine,’ and the more research we do, the more ways we find that tuning our nutrition can sometimes be superior to taking more pharmaceuticals.

While the idea of seeing food as a legitimate healthcare tool isn’t new, per se, there are some exciting new tools and platforms that leverage nutritional information and make it more accessible to the world. And that’s what we’re going to talk about on this episode.

Our first guest is Shireen Abdullah, CEO & Founder at Yumlish, who joined the StartUp Health community in 2019. Shireen’s platform puts a virtual nutritionist in your pocket, with a strong emphasis on boosting health literacy. She’s also worked very closely with the Air Force on workforce readiness. Turns out there are so many young people who are overweight and inactive that it’s hindering military recruitment and becoming a national security threat.

After Shireen we’ll hear from Victor Penev, CEO & Founder of Edamam, a Health Transformer since all the way back in 2013. Victor has made the world’s food knowledge more searchable through Edamam’s API so that users of platforms like NOOM and Virta Health can get personalized meal recommendations. We’ll also hear about their brand new integration with Open AI that brings a ChatGPT experience to the process of finding personalized meal plans.

Enjoy the episode!


FundersBecome a Health Moonshot Champion
Want more content like this? You can subscribe to the podcast as well as other health innovation updates at startuphealth.com/content.
Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.

Looking to break down health barriers? If you’re an entrepreneur or investor, contact us to learn how you can join our Health Equity Moonshot.
Passionate about Type 1 diabetes? If you’re an entrepreneur or investor, contact us to learn how you can join our T1D Moonshot.


Neolth Teams Up with NBA Star Kenny Thomas to Bring Mental Health Tools to Kids



According to some estimates, out of the HHS, nearly 50% of kids have experienced some kind of mental health challenge. And not just anxiety about an upcoming test or depression over a breakup, but persistent feelings that interfere with daily activities.

Health innovation companies have been on the case for years, including many from the StartUp Health community. They’re tackling the science – like what’s the best way to treat mental health challenges in teens – and they’re also tackling engagement. You can have the best tools in the world after all, but if a young person doesn’t want to get help, it’ll never go anywhere.

Enter Katherine Grill, PhD, CEO & Co-founder of Neolth, one of our guests on this podcast episode. She’s taken her doctorate in behavioral neuroscience and her experience as a clinician, combined with hundreds of interviews with young people, in order to build a platform that meets kids where they’re at – offering self-guided mental health support in a variety of forms and flavors.

Joining the podcast with us is former pro basketball player, Kenny Thomas. After spending 11 seasons in the NBA, Thomas became an entrepreneur and community advocate, with a focus on youth experiencing financial hardship via his own foundation. And now he’s throwing his influence behind Neolth in order to help young people, particularly those involved in sports, gain access to mental health services.

On this StartUp Health NOW episode, we’ll cover the ins and outs of the Neolth platform as well as some of Dr. Grill’s strategy behind working with a brand ambassador, which is somewhat unique in the world of early-stage health startups.

Let’s get into it.


FundersBecome a Health Moonshot Champion
Want more content like this? You can subscribe to the podcast as well as other health innovation updates at startuphealth.com/content.
Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.

Looking to break down health barriers? If you’re an entrepreneur or investor, contact us to learn how you can join our Health Equity Moonshot.
Passionate about Type 1 diabetes? If you’re an entrepreneur or investor, contact us to learn how you can join our T1D Moonshot.


These Founders Are Pairing AI + SDoH to Re-humanize Healthcare



Our episode this week was recorded during our StartUp Health Studio interviews at the recent HLTH conference in Las Vegas. At the event, a hot topic was how artificial intelligence, specifically generative AI, is going to fundamentally shift healthcare delivery. AI can help us comb through mountains of information and take action on data points that were previously hidden from view. But many people have a serious concern – even a fear – that AI will degrade the doctor-patient relationship and effectively dehumanize healthcare.

Our two guests today both joined the StartUp Health community earlier in 2023. They are pushing back against that narrative and suggesting with their companies that AI and big data can be leveraged to re-humanize healthcare delivery.

First we’ll talk with Nicole Cook, the CEO & Founder of Alvee, who is on a health moonshot mission to use AI-driven solutions to promote health equity and improve health outcomes for all. Cook reminds us that doctors are spending an inordinate amount of their time with a patient tapping away at a screen. The status quo is not working, so can new patient data tools help? Can they bring the right information to the surface at the right time and the right way, so healthcare providers can get back to making eye contact with patients?

What’s Cook is building at Alvee is resonating, as she went on to win the HLTH Startup Pitch Competition.

Next, we hear from Chris Turner, CEO & Co-founder at HealthBook+, who is attempting to create a fuller, more human picture of each patient using all available data including data from some nontraditional sources. HealthBook+ provides a simple-to-use, digital-first care platform which consolidates health data and keeps it private, as well as predicts conditions and recommends the next best health actions.

If the top line story for this episode is how data and AI could be used to create a more human electronic health record, the secondary story is about who can benefit from this technology.

Everyone’s talking about social determinants of health. This idea that we need to address the non-medical drivers of health, like access to fresh food and transportation. Healthcare providers care about these issues but don’t have the time or resources to analyze the data. That’s where Alvee Health and HealthBook+ can come in. Providing a fuller, more human analysis of patient data means taking into account important barriers to care and getting smart about how to overcome them.

So let’s get into it.


FundersBecome a Health Moonshot Champion
Want more content like this? You can subscribe to the podcast as well as other health innovation updates at startuphealth.com/content.
Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.

Looking to break down health barriers? If you’re an entrepreneur or investor, contact us to learn how you can join our Health Equity Moonshot.
Passionate about Type 1 diabetes? If you’re an entrepreneur or investor, contact us to learn how you can join our T1D Moonshot.