Tag Archives: Brain health

Exploring the Connection Between the Brain and Metabolism

SynchNeuro: How a Neurosurgeon Is Changing Cardiometabolic Care



Ever wonder where the next big breakthrough in health will come from? Sometimes, the most innovative solutions arise from the most unexpected places. This week’s podcast episode dives into the fascinating world of a neurosurgeon who’s revolutionizing glucose monitoring. Join us as we explore the groundbreaking work of Dr. Casey Halpern, co-founder of SynchNeuro, who is changing cardiometabolic care via the brain.

We discuss:

  • The unexpected connection between the brain and metabolism: How a neurosurgeon specializing in Parkinson’s disease came across a game-changing approach to glucose monitoring.
  • A non-invasive CGM for everyone: Learn about SynchNeuro’s innovative behind-the-ear EEG device that could make continuous glucose monitoring accessible and affordable for millions at risk of Type 2 diabetes and heart disease.
  • From physician to founder: Dr. Halpern shares his inspiring story as a doctorpreneur, leading the double life of a medical career and leading a cutting-edge health tech startup.
  • The future of cardiometabolic health: We explore how this new technology, combined with the rise of GLP-1 medications, could transform the way we manage and prevent diabetes and heart disease.
  • The science behind the breakthrough: A deep dive into the research connecting brain signals to appetite and blood sugar regulation.

Tune in to discover how SynchNeuro – a member of our Cardiometabolic Health Moonshot Community – is poised to reshape the landscape of cardiometabolic health and empower individuals to take control of their wellbeing.

 

For years, chronic health problems like heart disease and Type 2 diabetes have grown, becoming some of society’s biggest killers. Thankfully, there’s a generation of entrepreneurs tackling the issue from every angle. In the Cardiometabolic Health Moonshot Community, mission-aligned founders and CEOs collaborate to accelerate breakthroughs in cardiometabolic disease prevention, diagnosis, monitoring, management, and cures.
» Meet the Community

» Join the Community


Are you ready to tell YOUR story? Members of our Health Moonshot Communities are leading startups with breakthrough technology-driven solutions for the world’s biggest health challenges. Exposure in StartUp Health Media to our global audience of investors and partners – including our podcast, newsletters, magazine, and YouTube channel – is a benefit of our Health Moonshot Community Showcase Membership. To schedule a call and see if you qualify to join and increase brand awareness through our multi-media storytelling efforts, submit our three-minute application. If you’re mission-driven, collaborative, and ready to contribute as much as you gain, you might be the perfect fit.
» Learn more and apply today.

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Imaginostics: Brand New Technology for Preventative Health

Imaginostics Is Imagining Brand New Innovative, Non-Invasive Diagnostic Solutions for Health & Disease



What if a single scan could not only diagnose existing health issues but also predict future problems and help prevent them? That’s the groundbreaking vision behind Imaginostics, a startup co-founded by Codi Gharagouzloo, PhD. A new member of the StartUp Health community, Imaginostics creates innovative, non-invasive diagnostic solutions using breakthrough quantitative imaging biomarkers to provide new insight in health and disease.

In this episode, StartUp Health co-founder Unity Stoakes interviews Gharagouzloo during JPM Week in San Francisco to explore the science behind Imaginostics and the unique technology they’re developing to revolutionize preventative health. You’ll also hear Gharagouzloo’s fascinating founder journey, from a troublemaking youth to a physicist with a soul-deep passion for transforming healthcare.

With $5M raised and an FDA breakthrough designation in hand, Imaginostics is making waves. Don’t miss this inspiring story of innovation, passion, and the pursuit of better health for all.Tune in now!

 


Are you ready to tell YOUR story? Members of our Health Moonshot Communities are leading startups with breakthrough technology-driven solutions for the world’s biggest health challenges. Exposure in StartUp Health Media to our global audience of investors and partners – including our podcast, newsletters, magazine, and YouTube channel – is a benefit of our Health Moonshot Community Showcase Membership. To schedule a call and see if you qualify to join and increase brand awareness through our multi-media storytelling efforts, submit our three-minute application. If you’re mission-driven, collaborative, and ready to contribute as much as you gain, you might be the perfect fit. Learn more and apply today.

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Breaking News: Sinaptica's Noninvasive Neuromodulation Device Slows Alzheimer’s Disease in Year-Long Trial

Breaking News: Sinaptica’s Noninvasive Neuromodulation Device Slows Alzheimer’s Disease in Year-Long Trial



Hear the latest groundbreaking news in Alzheimer’s research. Sinaptica, a member of StartUp Health’s Alzheimer’s Moonshot Community, has announced significant results from its Phase 2 clinical trial testing the company’s noninvasive, personalized, precise neuromodulation designed to stop the progression of Alzheimer’s disease.

Ken Mariash, CEO of Sinaptica, joined us in the StartUp Health Studio to break it all down for us. As you’ll hear, the interview took place prior to the release of this data, which became public on October 31.

In this exclusive interview, you’ll learn:

  • Details on Sinaptica’s Phase 2 trial results show significant promise in slowing Alzheimer’s progression
  • The science behind Sinaptica’s technology
  • How personalized neuromodulation is revolutionizing brain health
  • The potential for proactive brain strengthening and repair
  • The impact on patients’ daily lives
  • The future of Alzheimer’s treatment

This episode is a must-listen for anyone interested in Alzheimer’s research, neuroscience, and the power of innovation to transform lives.


Are you ready to tell your story? Members of our Health Moonshot Communities are leading startups with breakthrough technology-driven solutions for the world’s biggest health challenges. Exposure in StartUp Health Media to our global audience of investors and partners – including our podcast, newsletters, magazine, and YouTube channel – is a benefit of StartUp Health’s PRO Membership. To schedule a call and see if you qualify to join and increase brand awareness through our multi-media storytelling efforts, submit our three-minute application. If you’re mission-driven, collaborative, and ready to contribute as much as you gain, you might be the perfect fit. Learn more and apply today.

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Old School + New School Tech = Big Impact

Old School Tech Makes Big Impact in Cognitive Care: Reporting from the Alzheimer’s Association International Conference



This episode of StartUp Health NOW throws out the tech buzzwords and dives into the power of seemingly simple solutions. We meet two innovative founders in our Alzheimer’s Moonshot Community who are using familiar technologies – the telephone and television – to tackle major healthcare challenges.

  • First up, Paul Campbell, CEO & Co-founder of Moneta Health, explains how their evidence-based dementia care program utilizes an “old school meets new school” approach, using AI plus the humble landline to reach a wider audience and overcome tech barriers for patients with early-stage dementia and Alzheimer’s.
  • Then, Bill Uniowski, CEO & Co-founder of Zinnia, shares how his company is creating smart video content specifically designed for people with advanced dementia, offering a calming and therapeutic experience that reduces the need for medication and improves lives for both patients and caregivers.

Join us for a refreshing look at how low-tech solutions can deliver high-impact healthcare.


Innovating in Alzheimer’s disease? Learn how you can join our Alzheimer’s Moonshot.

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An Insider’s Perspective on the Near Future of Alzheimer’s Care



“Academia is a great area and fosters innovation, but then taking that science and translating it into something that can actually impact human health has a number of challenges. So trying to understand what those barriers are and how we can help bridge them is something that we have been able to do at ADDF and in collaboration with StartUp Health.”

In this episode of StartUp Health NOW, we chat with Laura Nisenbaum, PhD, Executive Director of Drug Development at the Alzheimer’s Drug Discovery Foundation (ADDF). Organizations like ADDF are working to translate scientific research into real patient impact, particularly in the field of Alzheimer’s disease, by funding innovative ventures and supporting startups in the biotech space. Dr. Nisenbaum talks with us about new Alzheimer’s tests and therapeutics and pulls back the curtain on how ADDF supports startups.

Key Insights:

  • We are at a tipping point in Alzheimer’s. Our ability to predict and detect – and then treat – Alzheimer’s disease is growing faster than ever.

  • Dr. Laura Nisenbaum was involved in the launch of StartUp Health’s Alzheimer’s Moonshot, a collaboration with The Gates Foundation and ADDF, which is important for advancing research in the field of Alzheimer’s disease.

  • Academia fosters innovation, but translating scientific work into real patient impact poses challenges that need to be understood and bridged.

  • Venture philanthropy model enables funding for innovators who may not receive funding from for-profit companies, allowing for more risky endeavors.

  • The Diagnostics Accelerator challenges the research community to develop cutting-edge biomarkers and explore novel diagnostic technologies that will aid in Alzheimer’s diagnosis and clinical trial design.

  • The potential for AI to revolutionize Alzheimer’s research and diagnosis is evident in the funding and support for innovative companies in the field.

  • Focusing on the biology of aging, including inflammation and mitochondrial dysfunction, could be key in developing novel therapies for Alzheimer’s disease.

  • The field of Alzheimer’s research and care is at an amazing point with the first demonstration of some efficacy for drugs and a huge innovation curve from a biomarkers and diagnostics perspective.

  • We can now detect amyloid in the brain through blood tests, marking an amazing point of innovation in the field of Alzheimer’s research.

  • Pursue innovative ideas with great gusto and perseverance, and take advantage of the incredible network of mentors and collaborators to thrive in the biotech and startup space.

  • The momentum is building in the field of Alzheimer’s research, thanks to the support from organizations like ADDF.

 


 

Innovating in Alzheimer’s disease? Learn how you can join our Alzheimer’s Moonshot.

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AAIC RetiSpec & Sinaptica

How AI Is Creating an Inflection Point in Brain Health Innovation: Reporting from the AAIC



Join StartUp Health NOW for a powerful episode recorded live at the Alzheimer’s Association International Conference (AAIC)! We explore the exciting inflection point in Alzheimer’s research fueled by AI and machine learning.

Hear directly from passionate founders in the StartUp Health Alzheimer’s Moonshot Community:

  • Catherine Bornbaum, PhD, CBO at RetiSpec, fresh off the company’s $10M Series A, unveils a groundbreaking AI-powered device that analyzes the retina for insights into brain health.
  • Ken Mariash, CEO of Sinaptica Therapeutics, discusses using AI and neuromodulation to potentially slow Alzheimer’s and strengthen brain function in healthy individuals.

Discover:

  • How AI is unlocking a multi-modal understanding of the brain
  • The potential for revolutionizing treatment for all brain conditions
  • The cutting-edge technologies shaping the future of Alzheimer’s research

This episode is a must-listen for anyone passionate about brain health and the fight against Alzheimer’s!


Innovating in Alzheimer’s disease? Learn how you can join our Alzheimer’s Moonshot.

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Inside the Alzheimer’s Moonshot Impact Board: Fostering Collaboration for Alzheimer's Innovation

Gates Ventures’ Aishu Sukumar Is Fostering Collaboration on StartUp Health’s Alzheimer’s Moonshot Impact Board



Breaking Down Silos for Alzheimer’s Innovation: A Conversation with Aishu Sukumar of Gates Ventures

This episode of StartUp Health NOW welcomes Aishu Sukumar of Gates Ventures in another in our series of conversations with our Alzheimer’s Moonshot Impact Board.

  • A champion for collaboration: Explore Sukumar’s vision for leveraging data and fostering collaboration among Alzheimer’s innovators.
  • From research scientist to moonshot leader: Discover Sukumar’s unique career path that bridges science, business, and healthcare, taking her from Harvard Medical School and Berkeley to working at startups and then to Gates Ventures.
  • The power of a Health Moonshot Community: Learn how this initiative is uniting innovators to accelerate progress against Alzheimer’s.

This episode is for you if:

  • You’re passionate about finding a cure for Alzheimer’s.
  • You believe in the power of collaboration in tackling complex challenges.
  • You’re curious about the journeys of inspiring healthcare leaders.

Want even more about Alzheimer’s disease innovation?

Join us as we explore how Aishu Sukumar’s diverse background is shaping the future of Alzheimer’s research as a member of our Alzheimer’s Moonshot Impact Board.


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Gates Ventures, Kristina Malzbender: Insider the Alzheimer's Moonshot Impact Board

Gates Ventures’ Kristina Malzbender Joins Alzheimer’s Moonshot Impact Board



Hope on the Horizon: A New Era of Alzheimer’s Innovation

This episode of StartUp Health NOW dives deep into the fight against Alzheimer’s disease in the second in our series of conversations with our Alzheimer’s Moonshot Impact Board. Join us as we chat with Kristina Malzbender, the Associate Director, Health & Life Sciences, at Gates Ventures. Hear from this key leader about the concrete realities behind the optimism in Alzheimer’s innovation.

  • A century of relentless pursuit: Learn how the tide is turning after decades of dedicated research.
  • Early detection, slowed progression, and even potential cures: Explore exciting advancements in Alzheimer’s treatment.
  • Gates Ventures and the Diagnostic Accelerator (DxA): Find out how Gates Ventures and the Alzheimer’s Drug Discovery Foundation (ADDF) are supporting companies and academic researchers developing novel biomarkers and diagnostics for Alzheimer’s.
  • Introducing StartUp Health’s Alzheimer’s Moonshot: Discover a powerful collaboration aimed at accelerating progress

This episode is for you if:

  • You’re passionate about Alzheimer’s disease.
  • You’re curious about the latest advancements in dementia research.
  • You want to learn how you can contribute to the fight against Alzheimer’s.

Want even more about Alzheimer’s disease innovation?

Join us as we ignite hope for the future of Alzheimer’s innovation!


 

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Phyllis Ferrell Named Chief Impact Officer for StartUp Health’s Alzheimer’s Moonshot



In January, StartUp Health launched the Alzheimer’s Moonshot with support from the Alzheimer’s Drug Discovery Foundation (ADDF) and Gates Ventures. The Alzheimer’s Moonshot is an invitation to Health Transformers, Alzheimer’s funders, foundations, advocates, and innovators, as well as leading startups and research teams, to unite in pioneering comprehensive, collaborative approaches to Alzheimer’s disease.

The Alzheimer’s Moonshot Community is powered by StartUp Health and our Health Transformer University, an entrepreneurial mastery program and lifelong learning community for ambitious founders and funders who are solving the biggest health challenges of our time.

That brings us to our podcast guest this week. Phyllis Ferrell, DrPH, will serve as the Chief Impact Officer of the Alzheimer’s Moonshot and lead its Impact Board. Ferrell has three decades of related experience, most recently serving as the Global Head of Alzheimer’s and Neurodegeneration at Eli Lilly and Strategic Advisor to the Davos Alzheimer’s Collaborative. The Alzheimer’s Moonshot Impact Board will also include representatives from the ADDF, Gates Ventures, and a diverse group of stakeholders from industry, clinical medicine, academia, investment and patient and caregiver communities.

As we will discuss in the episode, shortly after Ferrell transferred from a marketing and sales role at Lilly to leading their Alzheimer’s division, her father was diagnosed with the devastating disease. She threw herself into the work and eventually became a leading voice in Alzheimer’s research and drug development. She’s served as a strategic advisor to multiple high-profile Alzheimer’s organizations, and now she’s marshaling her experience to lead StartUp Health’s Alzheimer’s Moonshot. We caught up with her to get a better understanding of where she sees this initiative going and why this is such a unique moment in time for Alzheimer’s innovation.

Enjoy the episode and then learn more about StartUp Health’s Alzheimer’s Moonshot at startuphealth.com/alzheimers.


Innovating in Alzheimer’s disease? Learn how you can join our Alzheimer’s Moonshot.
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Virtual Reality for Brain Health: Virtuleap’s New Platform Uses VR to Detect Cognitive Decline Early



Our StartUp Health NOW guest this week is Amir Bozorgzadeh, CEO & Co-founder of Virtuleap, a brain health company that joined StartUp Health in 2019.

Headquartered in Lisbon, Portugal, and expanding to Barcelona, Spain, Virtuleap improves brain health with VR. In this chat, Amir will walk us through their new platform – Cogniclear VR – that combines neuroscience with virtual reality games and activities to detect cognitive disorders. He’ll explain how VR can play an important role in the diagnosis of Alzheimer’s and other dementias, why VR needs to be applied with care in health, and where virtual reality is going next.

Enjoy!


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